Lessee...I still read Penny-Arcade out of habit, even though it's rarely funny anymore. Vgcats is awesome, I like PvP, Marilith is so lame it's good, and the best thing about Megatokyo is that every few months I can go to the site, hit "back" three times and end up where I started months before (oh wow, Piro has low self-esteem and five girls after him! What crazy plot twist will he throw at us next??!)
Anyway, of the comics that I read that I don't think anyone's mentioned:
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(......fuck, I don't know how to do hypertext)
http://www.pennyandaggie.com - The drawing is above average but the story and writing's pretty scattershot; there's not a whole lot of clear progression and and some of the punchlines are random and forced. Plus, I'm pretty sure to get the full effect you have to be a teenage girl.
http://www.schlockmercenary.com - A pretty funny space-opera that's ostensibly a "hard" sci-fi. I couldn't tell you whether it is or isn't as I'm not really familiar with "teh science". The art is servicable and the story moves at a pretty good clip, the only real problem I have is that every character has the same dry sense of humor. But then, that's my second favorite type, so I should probably quit bitching.
http://www.errantstory.com - A really good(imo) fantasy webcomic. The art is nice, and the story, dialogue, ect are all well above average, plus nudity. It can drag at points though. The author's previous comic, Explotation Now, is arguably better/worse, though obviously not drawn as well. But with more nudity.
http://www.themidlands.net - Not sure why I still read this. Oh yeah, lesbians. Basically, you've got really strangled political commentary in some pseudo-sci-fantasy setting. Tries to be deeper than it really is, and lesbians. The art's gone from utter crap to bizare chibi to "pretty good looking from one angle but really 2D and lacking depth", the author is colorblind (and oh god it shows) but doesn't shy away from nudity, lesbians, or lesbian nudity. Perhaps I overemphasize.
Maybe if you know your true love is about to move away to college or something, you can stick this shit in the stereo and make the moment last while at the same time listening to pussies whine about bitch shit. Just like you.